Sodium Tetradecyl Sulfate

Research use only, not for human use.

Sodium Tetradecyl Sulfate is a detergent sclerosant with antithrombotic effects and commonly used for the treatment of varicose veins.

Sodium Tetradecyl Sulfate is a detergent sclerosant with antithrombotic effects and commonly used for the treatment of varicose veins.(In Vitro):Proteins C, S and antithrombin (AT) were assayed in normal plasma treated with increasing concentrations of Sodium Tetradecyl Sulfate. High concentration (>0.6%) Sodium Tetradecyl Sulfate significantly destroyed proteins C, S and AT. Sodium Tetradecyl Sulfate potentiated the anticoagulant effect of APC. Sodium Tetradecyl Sulfate mimicked AT and demonstrated significant anti-Xa and anti-IIa activity. STS demonstrated a weak anticoagulant profile to heparin. It also significantly potentiated the anticoagulant effect of heparin.(In Vivo):i.v. + p.v. injection of Sodium Tetradecyl Sulfate and hydroxy polyethoxy dodecan provided a high degree of efficacy as regards vein occlusion. On the other hand, i.v. + p.v. injection induced a severe inflammation and necrosis of the tissues surrounding the sclerosed vein.

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Tetradecyl sodiuM sulfate

Others

Other Targets

NMDA

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1191-50-0

316.43

C14H29NaO4S

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (316.03 mM)

[Na+].CCCCCCCCCCCCCCOS([O-])(=O)=O

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(-20℃)

With Ice Pack

≥ 2 years